My own mom favored Scrabble and various card games...we're talking Cribbage and poker. But.
There was a point very near the end of her days when I was talking to her about Star Wars Galaxies, and what it was like for me to have such amazing adventures in that world. I don't think she understood half of what I was saying, but there was this interested spark.
There was so little she could do, physically, but she had a great imagination, and a rich inner life. I wished I could bring my computer over, and let her create a character. She would have loved all of the choices of hair color and styles, and the cosmetic options.
What really captured my imagination was that she would so enjoy being able to run through a sunlit world, completely unfettered by any physical ailments. She could be as vibrant as anyone around her. She would have been so beloved by other players with that warm, funny, sassy personality. God help everyone when she hit the cantina.
My own character early on was a Master Doctor. It was a powerful experience for me to be able to cure anyone of anything, when I spent so much time in hospital rooms worrying that I would lose this little person. Always that fear. You can imagine what it meant to me that I could also bring someone back to life. Not possible in the real world, but how I have always loved saving people in game.
You might give your mom a shot at creating a character in your favorite game. Even if she doesn't end up playing, I think there's a pretty good chance it will be a good gaming experience for both of you.